There is a subtle, but powerful, connection in this verse between the way we perceive (regard) others and the way we perceive Christ.

Some translations, rather than “a worldly point of view”, say “the flesh”. Life is a choice between two paths; the path of righteousness and the path of wickedness. Like an angel on one shoulder and a demon on the other, both of these paths are possible within a human soul. Divine and internal powers are making the case for each. 

You are the referee and get to determine who wins the battle. That is the great role of your life. 

In 2 Corinthians 5, Paul is giving an account of the life he (and his brethren) have lived. They used to regard Christ according to the flesh. Meaning, they saw Him as a Cosmic Vending Machine, a source to something greater. And they do this no longer. They now choose to see Him from a Godly point of view, according to the spirit.

The natural result of this is that they no longer regard others from a worldly point of view. 

How we perceive Christ trickles down into how we perceive others. The way we treat others is as indicative of the way we regard Christ as it is about the other person. It reveals our perceptions. When we love Christ well, we will love others. When we celebrate Christ, we will celebrate others.

We are all members of the body, with Christ as the Head. We cannot fully love one another (or listen to one another or trust one another) without first regarding Christ from the right point of view. He is the standard bearer. How we perceive Christ affects how we treat others.

“So from now on we regard no one from a worldly point of view. Though we once regarded Christ in this way, we do so no longer.”
– 2 Corinthians 5:16